Synthroid Can Cause Allergic Reactions and Sensitivity
He was put on continuous cardiac and vital sign monitoring throughout the desensitization process and emergency medications of parenteral hydrocortisone, chlorpheniramine and adrenaline were prepared at bedside in case he developed any allergic reaction. The desensitization of levothyroxine was successful without signs or symptoms of allergy. He was discharged well five days after admission with 100 mcg of oral levothyroxine. The incidence of hypothyroidism within a year post RAI therapy in Malaysia is 32.9%.1 The standard treatment for hypothyroidism is oral levothyroxine (LT4). SYNTHROID® (levothyroxine sodium) tablets, for oral use is a prescription, man-made thyroid hormone that is used to treat a condition called hypothyroidism in adults and children, including infants.
He was initiated with intravenous levothyroxine at a daily dose of 100 mcg for four consecutive days as he was severely hypothyroid. This was done with an initial test dose of 1 mcg administered as a slow bolus over five minutes, followed by the remaining dose given over another five minutes with continuous cardiac and vital sign monitoring. He had no immediate or delayed hypersensitivity reaction to the intravenous preparation. A study evaluated the effect of long-term thyroid hormone therapy on bone mineral density in 196 women (mean age, 74.4 years) compared to a control group comprised of 795 women (mean age, 72.1 years). The mean daily thyroxine dose was 1.99 mcg/kg (range, 0.3 to 6.6 mcg/kg) with a mean duration of therapy of 20.4 years (range, less than 1 to 68 years). Women taking daily doses of 1.6 mcg/kg or more had significantly lower bone mineral density levels at the ultradistal radius, midshaft radius, hip, and lumbar spine compared to controls.
Fluoride was added to nearly all public drinking water in the United States in the 1950s as a public health measure meant to minimize tooth decay, and we continue to fluoridate most of our water today. Our detox pathways may become overwhelmed and overburdened, and we end up with a toxic backlog. Toxins may build up and circulate in our bodies, or become stored in our fat instead of being properly excreted. This often results in multiple symptoms, as well as reactions to substances that are normally harmless. The common practice of switching to other commercially available preparations of levothyroxine with different excipients will usually resolve the issue.2 However, if this strategy fails, desensitization to levothyroxine should be considered. Therefore, we performed an oral desensitization with multiple doses of the drug preparation.
Sneaky Thyroid Toxins
Typically only the word “fragrance” will appear on the ingredient labels, and exact ingredients in these formulations are not usually disclosed. We live in a world filled with plastic, and honestly, it’s hard to completely eliminate it from our lives these days! We are exposed to so many toxins every day – both inside and outside our homes (some are obvious, some less so). Written informed consent was obtained from the patient for publication of this abstract and any accompanying images.
Does Synthroid interact with my other drugs?
1 This inability to detox properly can trigger or worsen autoimmune symptoms, as these chemical exposures can trigger immune dysregulation. 2 This is why we need to be especially diligent when it comes to addressing chemical exposure in our day-to-day lives. Her endocrinologist prescribed her other brands of levothyroxine, and the patient reported the same reaction. We report a case of drug rash induced by levothyroxine and currently oral desensitization. Certain foods and medications can interfere with the way your body absorbs or processes Synthroid.
If you are concerned, keeping a daily diary of symptoms may be helpful. Make sure to document any hay fever symptoms, hives or itching, and digestive system symptoms you have, as well as how you are feeling overall. An allergy may result in TSH levels that rise (and consequently, symptoms of hypothyroidism), but there are many possible causes if your thyroid medication isn’t working.
Liver Congestion and Thyroid Disease
These improvements can be life-changing for people, and my clients and readers who follow liver support protocols are always amazed at their results. I’ve personally repeated my own Liver Support protocol at various times in my life, and right around age 40, I remember feeling like I was “just getting older”… my skin, weight, and mood weren’t quite what they used to be because of perimenopause. Angry thoughts that I was holding onto released, my skin looked younger, I had more energy and finished projects that were on the “backburner” for years, and I effortlessly lost around 5 pounds. Makeup is supposed to enhance our natural beauty, but for many of us, it’s secretly undermining our health.
- There are several tests that can be done if lactose intolerance is suspected, such as a lactose tolerance test, hydrogen breath test, or, in children, a stool acidity test.
- The mean daily thyroxine dose was 1.99 mcg/kg (range, 0.3 to 6.6 mcg/kg) with a mean duration of therapy of 20.4 years (range, less than 1 to 68 years).
- Allergy testing is available for acacia, though the allergy may be suspected in those who have previously been diagnosed with tree or grass allergies.
- If your TSH fluctuates from high to low, there are many potential causes, but hypersensitivity to Synthroid is one possibility.
- Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.
- Synthroid can be given to infants and children who cannot swallow whole tablets by crushing the tablet and mixing the freshly crushed tablet in a small amount (5 to 10 mL or 1 to 2 teaspoonfuls) of water and immediately giving the misture by spoon or dropper.
Studies looking at the incidence of acacia sensitivity are few, but it appears that there is a particularly high rate of sensitization among people living in Iran and surrounding countries, as well as the Philippines. Scratched non-stick pans are a common source of aluminum toxicity, which is why I recommend using stainless steel pans, ceramic cookware, or cast iron pans. It’s important to note that mold can act as both a toxin and an “infection.” Let me explain. When we are exposed to mold over a period of time, mold can colonize our sinuses, lungs, and/or gut. Avoiding environmental mold is always important, but in this case, people may also need to use antifungals to remove the mold colonization. I also highly recommend investing in a quality air filter, such as the AirDoctor or Jaspr, to help purify your living environment of airborne molds and other allergens.
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Some side effects of levothyroxine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Acacia is a family of shrubs and trees, and it is used as an ingredient (acacia gum) in some medications, including Synthroid brand levothyroxine, to provide form and shape to tablets. Some people who have pollen allergies and hay fever—especially to tree and grass pollens (such as ryegrass pollen)—may also have an allergy to acacia, even when it’s an ingredient in a medication. Symptoms ranging from a runny nose to a rash and/or hives, to synthroid mood abdominal pain may occur, and it may take some time to realize it’s the drug rather than something else that’s responsible.
Before taking this medicine
With a corn allergy, symptoms may range from hives to hay fever, to anaphylaxis. With celiac disease, symptoms may suggest an intolerance, such as bloating, abdominal pain, or constipation, but may also include less common symptoms ranging from anemia to infertility. An allergic reaction to Synthroid is most often diagnosed based on history, though allergy tests are available for acacia. Management most often includes switching to another brand of levothyroxine, and, fortunately, there are other brands of the drug with different ingredients that may be effective. Lead can be found in old paint, pipes, and some cosmetics, and chronic lead exposure has been linked to hypothyroidism. 29 Lead can impact thyroid function by blocking iodine uptake and affecting thyroid hormone production.